tag:blogger.com,1999:blog-8859456735165996893.post1253105134896827483..comments2024-03-28T02:36:04.078-07:00Comments on Health Correlator: Daniel Suelo, the man who quit money, seems remarkably healthyNed Kockhttp://www.blogger.com/profile/02755560885749335053noreply@blogger.comBlogger17125tag:blogger.com,1999:blog-8859456735165996893.post-53172933959671080202015-04-21T22:10:44.218-07:002015-04-21T22:10:44.218-07:00The Man Who Quit Money: An Interview with Daniel S...<a href="http://www.becomingminimalist.com/the-man-who-quit-money-an-interview-with-daniel-suelo/" rel="nofollow">The Man Who Quit Money: An Interview with Daniel Suelo</a>js290http://www.becomingminimalist.com/the-man-who-quit-money-an-interview-with-daniel-suelo/noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-55548991302213623352012-09-16T09:42:33.189-07:002012-09-16T09:42:33.189-07:00Thanks Yan. If you are referring to the topic of c...Thanks Yan. If you are referring to the topic of cholesterol, that’s the topic of my next post. It should come out tomorrow.Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-32224999202925720782012-09-15T00:35:52.533-07:002012-09-15T00:35:52.533-07:00I appreciate your post, I have book marked this in...I appreciate your post, I have book marked this internet site so ideally I’ll see much more on this subject in the foreseeable future!<br /><br />Regards,<br /><a href="http://yan-katsnelson.blogspot.in/" rel="nofollow">Yan Katsnelson</a><br />Yan Katsnelsonhttp://vimeo.com/47666292noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-4210440105147679412012-09-14T08:37:51.899-07:002012-09-14T08:37:51.899-07:00The HDL story an example of medical wishful thinki...The HDL story an example of medical wishful thinking.<br /><br />I became interested in this as <br />i) my own level is 3 mmol/L<br />ii) my MD encouraged me to statinise<br />iii) I read the Gaziano paper<br />iv) found the Framingham graph relating CAD risk to values of HDL & LDL (joint distribution)<br />http://www.lipidsonline.org/slides/slide01.cfm?q=framingham&dpg=19 <br /><br />I concluded there was no reason to take statins, as reducing LDL by some points made little difference to my "Framingham Risk".<br /><br />I was also found out that values of >= 3 mmol/L HDL occur in about 2% of the population, so in this respect I am an outlier.<br /><br />I never accepted the notion of HDL being protective, as none of my MDs did - they preferred to focus on LDL levels being risky.<br /><br />NO Doc (in my experience)who wishes to prescribe a statin accepts the implications of the data represented in the Framingham joint distribution histogram above.<br /><br />High HDL is a MARKER of low risk, it is not in itself "protective".<br /><br />(As far as seeing myself as being at immediate risk of Heart Death, my TAG is 0.7 mmol/L and HsCRP is 0.7 mg/l.)<br /><br />SlainteLeonRoverhttps://www.blogger.com/profile/01484097018449402128noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-63453377553455342032012-09-13T12:02:57.914-07:002012-09-13T12:02:57.914-07:00Never thought someone can live a lifestlye like th...Never thought someone can live a lifestlye like that for so long.<br />I'm checking his blog right now, not bad!Lasik specialisthttp://www.worldclasslasik.comnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-2030175492403824952012-09-13T07:37:58.914-07:002012-09-13T07:37:58.914-07:00Hi Tom. Yes, I think that the article you linked i...Hi Tom. Yes, I think that the article you linked is one of the best I’ve seen recently on lipids. It highlights the fact that the lipids story is complex and full of puzzles. Here are some interesting quotes from that article:<br /> <br /> “The study’s authors emphasize that they are not questioning the well-documented finding that higher HDL levels are associated with lower heart disease risk.”<br /><br /> “Now it seems that instead of directly reducing heart disease risk, high HDL levels may be a sign that something else is going on that makes heart disease less likely.”<br /><br /> I find these statements to be fairly reasonable. Instant release niacin may play indirect roles, such as boosting growth hormone release, that have cardio-protective effects.<br /><br /> Here is another interesting quote from the article, related to LDL: “… gene variations that raise LDL increase risk and those that lower LDL decrease risk. The gene effects often were tiny …”<br /><br /> Talking about complex associations that are part of the big puzzle, here is another one – in men, free testosterone is strongly and negatively associated with intima-media thickness:<br /><br /> http://www.nature.com/ijo/journal/v27/n7/fig_tab/0802292f1.html<br /><br /> Also, there are many people who suffer from familial hypercholesteromia, and who have high HDL and also large LDL particles, and still develop CVD markers relatively early in life.<br /><br /> Life is not simple!Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-20059145927878556932012-09-12T17:47:14.384-07:002012-09-12T17:47:14.384-07:00Thanks Ned. Were you able to look at this HDL stud...Thanks Ned. Were you able to look at this HDL study from a few months ago which claime to cast doubt on high HDL being protective? <br /><br />http://www.nytimes.com/2012/05/17/health/research/hdl-good-cholesterol-found-not-to-cut-heart-risk.html?_r=2&hpTom Hallnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-86079725847011528472012-09-12T09:20:42.886-07:002012-09-12T09:20:42.886-07:00"... There are credible studies suggesting th..."... There are credible studies suggesting that a high HDL is protective, but not one achieved through drug interventions..."<br /><br />I am dubious about drug-based modification of most health markers. That includes markers such as blood pressure, which are widely accepted as being health outcomes rather than markers.<br /><br />For example, see:<br />http://www.nejm.org/doi/full/10.1056/NEJMoa1001286<br /><br />In this study, a group of diabetics with elevated blood pressure had their blood pressure reduced to recommended levels through drugs, while another was an untreated control group.<br /><br />After nearly 5 years, the cardiovascular outcomes between the two groups were the same, but the treatment group suffered many drug side effects. <br /><br />Not surprising to me, since hypertension is usually of unknown origin. There is some recent speculation that high CRP is a cause. In that case, it ia marker rather than a primary outcome, and lowering blood pressure without treating the underlying cause does no good.<br /><br />It's like painting your lawn green instead of watering it.David Isaakhttps://www.blogger.com/profile/04928598446742324391noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-10089672248077573662012-09-12T07:11:01.743-07:002012-09-12T07:11:01.743-07:00I’d bet that the “Suelo approach” would improve he...I’d bet that the “Suelo approach” would improve health markers in most people, including CVD markers. It may well be more effective than instant-release niacin at that :-)Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-27814680081166055842012-09-12T07:08:24.547-07:002012-09-12T07:08:24.547-07:00Related to my comment above in response to Tom’s, ...Related to my comment above in response to Tom’s, here are a couple of quotes from the study:<br /><br /> “Clinical trials of the high density lipoprotein raising agent niacin have shown a reduction in coronary events …”<br /><br /> “… we classified trials according to the following classes of intervention … niacin combinations with a statin, fibrate, or resin …”<br /><br /> Apparently instant-release niacin only interventions were not considered in the analysis. Again, probably because few people are willing to subject themselves to the “flush” resulting from taking instant-release niacin.Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-83528491272253776872012-09-12T07:02:02.858-07:002012-09-12T07:02:02.858-07:00Hi Tom. Making assertions about variance explained...Hi Tom. Making assertions about variance explained based on a meta-analysis is problematic. Still, raising HDL naturally seems like a better idea than via drugs. There are credible studies suggesting that a high HDL is protective, but not one achieved through drug interventions – with one exception, mega-doses of instant-release formulations of the vitamin niacin. Almost nobody does this, however, because of the flush.Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-714837275293135142012-09-10T12:01:28.188-07:002012-09-10T12:01:28.188-07:00Hey Ned,
What do you think of this study: http://...Hey Ned,<br /><br />What do you think of this study: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645847/<br /><br />Is all this fear of LDL reasonable?Tom Hallnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-21624427957614723722012-09-06T09:05:10.318-07:002012-09-06T09:05:10.318-07:00The second reviewer really got his panties in a bu...The second reviewer really got his panties in a bunch. It was hard for me to understand why he found this so threatening...until I checked out his other reviews and found this:<br /><br />'I can't add much to the many 5-star reviews already posted without being redundant but I will point out that if your reading time is tight the heart of this fine book is to be found in chapters 6 thru 9. Read it all if possible but in those chapters you will discover when and how, for the first time in history, the soul of the Left emerged in all its ugly fury. Disturbing to read about and contemplate what was done to people in the name of "hope and change" but the blood flow began then and continues unabated today. Coulter presents a riveting if necessarily brief history lesson seasoned with her caustic wit and razor-sharp sarcasm. If you can find time to read only one book this summer this is one you should seriously consider; Ann Coulter at her illuminating and fearless best!' <br /><br />So I suppose bringing up our hunter-gatherer ancestors with him won't help, as he probably also denies evolution.David Isaakhttps://www.blogger.com/profile/04928598446742324391noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-26678479121691421352012-09-03T08:20:46.013-07:002012-09-03T08:20:46.013-07:00Parasites are the people who can magically create ...Parasites are the people who can magically create principal out out of thin air, loan it to us, and expect to be paid back with interest.js290http://www.youtube.com/watch?v=l37RhdFGVsMnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-5520323533376620732012-09-03T05:20:23.664-07:002012-09-03T05:20:23.664-07:00Anonymous said...
Interesting, no money, yet ...<i><br />Anonymous said...<br /><br /> Interesting, no money, yet he maintains a blog?<br /> How?<br /></i><br /><br />It's said in the article, he goes to public libraries and setting up a blogger account is free. <br />gallier2https://www.blogger.com/profile/04285836062429366578noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-57891115776909363732012-09-03T05:06:33.913-07:002012-09-03T05:06:33.913-07:00Regarding a comment about his being a "parasi...Regarding a comment about his being a "parasite," I find that ridiculous. He is contributing to the conversation as to what it means to be human...Also, think we could debate what is more parasitic, destroying the earth with guns and oil and money or living a quiet life?<br /><br />Unsustainable? Probably true now, but mankind lived this style successfully for at least tens of thousands to millions of years, depending on when you want to start counting. Will we modern humans do as well?<br /><br /><br />dianaeddhttps://www.blogger.com/profile/13970503797750588054noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-23030082537365406752012-09-03T04:47:07.405-07:002012-09-03T04:47:07.405-07:00Interesting, no money, yet he maintains a blog?
Ho...Interesting, no money, yet he maintains a blog?<br />How?Anonymousnoreply@blogger.com