tag:blogger.com,1999:blog-8859456735165996893.post8515366893209738201..comments2024-03-28T02:36:04.078-07:00Comments on Health Correlator: Blood glucose variations in normal individuals: A chaotic messNed Kockhttp://www.blogger.com/profile/02755560885749335053noreply@blogger.comBlogger20125tag:blogger.com,1999:blog-8859456735165996893.post-19121725286957538182017-03-31T05:54:46.259-07:002017-03-31T05:54:46.259-07:00I haven't researched this lately, but my under...I haven't researched this lately, but my understanding was that yes, different people would have different BG responses to the same food, but the *relative* responses would be similar, with some exceptions. In other words, A might go up 10 points with food X and 20 points with food Y. But B would go up 25 points with food X and 50 points with food Y.<br /><br />BTW, anyone who got too much of people named A, B, and C, would enjoy Stephen Leacock's piece in Literary Lapses: http://www.online-literature.com/stephen-leacock/literary-lapses/40/. I giggle whenever I reread it.Gretchenhttps://www.blogger.com/profile/17019921800841883073noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-83619617267087781442017-03-30T20:09:56.039-07:002017-03-30T20:09:56.039-07:00Remember the "glycemic index"? (a dietar...Remember the "glycemic index"? (a dietary approach that ranked foods according to the glucose spikes they produced (maybe the area under the curve rather than the spikes).<br />In view of the wide variations of BG response to food input, I wonder if the glycemic index makes any sense: you could give exactly the same food to two individuals and their BG response could be very different, destroying the whole idea of ranking foods by their glycemic index. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-39405585128942280912017-02-06T14:47:03.289-08:002017-02-06T14:47:03.289-08:00Normally the areas under the curve (AUCs) are prop...Normally the areas under the curve (AUCs) are proportional to the amplitude of the spikes, but more so to the HbA1c’s. The HbA1c’s in this study varied from 4.3 to 5.4 percent.Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-66168073730203312912017-02-02T16:48:36.691-08:002017-02-02T16:48:36.691-08:00Was the insulin response in these folks measured? ...Was the insulin response in these folks measured? Just because these BG responses are common does not mean they are normal or healthy. ON the Jocko podcast Dr. Peter Attia recently discussed the goal to minimize BG spikes and that the true goal was to minimize insulin area under the curve. Accepting the premise that these spikes are harmless seems unsupported and may well mean more are close to ill health than realized. For me intermittent fasting and weight lifting have improved blood glucose control. I'm Thin and low carb but formerly desk bound for 20 years. I Don't take comfort from this analysis but will continue trying more fasting and lifting to see better BG numbers. Colleen Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-55966461565590982392017-01-31T11:21:06.224-08:002017-01-31T11:21:06.224-08:00The title of the chart says two days, but the time...The title of the chart says two days, but the times indicated are only for one.<br /><br />Are both days overlaid?Tucker Goodrichhttps://www.blogger.com/profile/09455436946187786398noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-37449766763240111582017-01-31T09:57:42.049-08:002017-01-31T09:57:42.049-08:00"So, we can also safely assume that they were..."So, we can also safely assume that they were somewhat "desensitized" (in terms of glucose response) to those types of foods. Someone who had been on a low carbohydrate diet for a while, and who would thus be more sensitive, would have had even wilder blood glucose variations in response to the same meals."<br /><br />why does this happen?<br /><br />Should low carbers take actions to mitigate the wilder glucose response? If so, what should they do?<br /><br />thanks for re-posting this.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-76263674228230764982017-01-30T17:41:56.582-08:002017-01-30T17:41:56.582-08:00Hi Ned,
I agree that there's a lot of individ...Hi Ned,<br /><br />I agree that there's a lot of individual variation in BG levels. But I've always wondered if the people with the very high postprandial levels in Christiansen's study went on to develop diabetes with age.<br /><br />Today, more and more people who can afford it, even those without diabetes, are using continuous glucose monitors. It would be interesting to pool the results from the CGMs as Christiansen did.Gretchenhttps://www.blogger.com/profile/17019921800841883073noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-71021647771992443032015-07-05T18:41:11.347-07:002015-07-05T18:41:11.347-07:00Hi Ned
I’ve been trying to get figures for blood s...Hi Ned<br />I’ve been trying to get figures for blood sugar distribution in the “normal” population (i.e. those without diabetes or pre-diabetes). I realise that the figures are up and down and all over the place, as in the graph in your article. What I want to know what percentage of people have average blood sugars in the 51-60 range, the 61-70 range, the 71-80 range, the 81-90 range, the 91-100 range. Ideally, I would like this not just for our “European” cultures, but also for those still following their “pre-MacDonalds” eating patterns (eg, people from Japan, maybe even Okinawa). <br />I am aware of the fact from my experience that some people seem to have blood sugars that tend to settle into the lower range between 1-3 hours after eating (and often depending on what they ate, too). Others, however, seem to settle into the mid or higher range of people who don't have blood sugar levels in the pre-diabetes or diabetes ranges.<br />I also realise that there may well be a variety of factors that determine how blood sugars move for individuals (including genetics, epigenetics [and this may be a significant factor, I suspect], pre-birth nutrition, early nutrition, what's happening endrchronoligically, and other facts as well).<br />I'm still keen to find out any trends that are known.<br />Also, I remember reading somewhere (possibly Purnell's History of the Second World War), that Japanese soldiers were still operating on blood sugar levels where European soldiers would have been comatose. If true, this is interesting.<br />FrankFrank Neillnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-61009771677468463012014-04-08T05:37:54.814-07:002014-04-08T05:37:54.814-07:00This comment has been removed by a blog administrator.angelaposteahttp://www.steroids-online.netnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-39304556006900565222013-12-10T03:22:03.908-08:002013-12-10T03:22:03.908-08:00This comment has been removed by a blog administrator.Anonymoushttps://www.blogger.com/profile/13367868683316914505noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-32614792203676715102013-10-09T13:10:04.962-07:002013-10-09T13:10:04.962-07:00It's good that people are recognizing that the...It's good that people are recognizing that there isn't a single range that is "normal" for blood sugar. I have non-diabetic Reactive Hypoglycemia can my normal range is 145-180. If I get below 140, I know I'm getting too low. If I followed the accepted "normal" range, by the time I got my sugar down to where it was supposed to be, I would be passed out. Other factors need to be taken into account before determining what your "normal numbers" are. I have an extremely high metabolism; I eat around 5,000 calories a day. Each individual is different. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-27774893176447238142013-07-15T05:56:22.670-07:002013-07-15T05:56:22.670-07:00Thank you for this information, I believe just as ...Thank you for this information, I believe just as your statistics show that blood glucose levels vary greatly among healthy people. <br /><br />The ADA says up to 100 can be consider normal fasting blood sugar where as other websites will say it should not be above 90 fasting. <br /><br />There is no cookie cutter approach to what is "normal" blood sugar levels, this is the same problem we have with BMI being used as a measure of obesity. <br /><br />Correlation does not equal causation and this why only a holistic assessment of an individuals health can tell us if they are healthy. Many who are called "diabetic" today are probably not. There is a diabetes epidemic in the West http://type2diabetesdietplan.blogspot.com/2013/06/what-can-help-with-diabetes-explosion.html<br />but we must be careful with assuming 100mg/dl fasting is in fact Pre diabetes.diabetes blue foothttp://diabetesfeetswollen.blogspot.com/2013/06/why-are-my-feet-blue-with-diabetes.htmlnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-76113629408956920662012-04-10T13:57:54.834-07:002012-04-10T13:57:54.834-07:00Four spam comments above deleted.Four spam comments above deleted.Ned Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-2464207682551352442011-12-15T00:04:57.732-08:002011-12-15T00:04:57.732-08:00This comment has been removed by a blog administrator.viagra substitutehttp://buyviagracheapmedicgeneric.co.uknoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-19334005006921085632011-10-20T06:25:45.823-07:002011-10-20T06:25:45.823-07:00This comment has been removed by a blog administrator.viagra for salehttp://buyviagragenericonlineexpress7x24.comnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-19890103934064672032011-04-01T08:20:21.986-07:002011-04-01T08:20:21.986-07:00This comment has been removed by a blog administrator.generic viagrahttp://www.iservepharmacy.comnoreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-90055789641197154912011-03-29T07:34:13.252-07:002011-03-29T07:34:13.252-07:00This comment has been removed by a blog administrator.generic viagrahttp://www.xlpharmacy.com/noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-6933015675424789422010-05-03T06:09:44.607-07:002010-05-03T06:09:44.607-07:00Justin:
I think you are right about car commuting...Justin:<br /><br />I think you are right about car commuting in general. I would also place in that category stressful online interactions (e.g., flaming).<br /><br />We experience too much stress while sitting down. I would recommend at least standing up and walking a bit, after a stressful situation.<br /><br />Indeed, a genetically programmed stress-fight/flight response, without anything like fight/flight cannot be too good for us.<br /><br />By the way, cortisol levels seem to get much more elevated in response to stress after a hyperglycemic meal than after a meal rich in protein or fat. This needs a separate post, but it makes sense to avoid refined carbs or sugars before that commute.<br /><br />Chris:<br /><br />Some of those folks who experience ketonuria (ketones in the urine) in the morning, also have high fasting glucose levels. The cause is physiological (or benign) insulin resistance.<br /><br />Physiological insulin resistance is also common after heavy exercise. My goal with the post is to show that the numbers vary a lot, so there is no need to panic due to certain readings.<br /><br />Having said that, you (and Jenny) are absolutely right about the problems associated with elevated blood glucose levels. Those levels are also associated with decreased lifespan:<br /><br />http://healthcorrelator.blogspot.com/2010/04/blood-glucose-control-before-age-55-may.htmlNed Kockhttps://www.blogger.com/profile/02755560885749335053noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-88558146619649214032010-05-02T06:49:33.542-07:002010-05-02T06:49:33.542-07:00Ned,
The question we should be asking isn't w...Ned,<br /><br />The question we should be asking isn't whether these people are diagnosed with diabetes, both of which are based on arbitrary and unjustifiably high cut-off points. The more relevant question is what blood sugar levels have been shown to cause health consequences and complications normally associated with diabetes. <br /><br />Jenny Ruhl has written about this extensively on her site, Diabetes 101. <a href="http://www.phlaunt.com/diabetes/14046782.php" rel="nofollow">This article</a> explains why the diagnostic criteria for diabetes are basically useless for preventing complications due to high blood sugar. While it may be "common" for blood sugar to rise above 150 mg/dl even in healthy subjects, that doesn't mean it's normal or healthy.<br /><br />In fact we know from studies that blood sugar >150 mg/dl an hour after eating strongly predicts heart attack. We also know that there's a very tight correlation between heart attack risk and A1c levels at as low as 4.6%. See <a href="http://www.phlaunt.com/diabetes/15945839.php" rel="nofollow">here</a> for more info.<br /><br />So it seems to me that while these fluctuations you describe may be common, elevated blood sugar readings above 140 mg/dl an hour after meals are certainly something to avoid.Chris Kresserhttps://www.blogger.com/profile/16374375198215570796noreply@blogger.comtag:blogger.com,1999:blog-8859456735165996893.post-401756959458331332010-05-02T06:33:11.269-07:002010-05-02T06:33:11.269-07:00Ned,
Good post. It would be interesting to see w...Ned,<br /><br />Good post. It would be interesting to see what the serum blood glucose response would look like during a normal "American" commute to or from work. I bet catecholamine response to the stress of the commute would cause some significant fluctuations in blood glucose. It makes my wonder about the potentially damaging effects of chronic fight/flight response without significant physical activity component to go along with this hormonal response. I am starting to think I should rate the invention of the automobile right up there with agriculture as one of the biggest mistakes made by human beings. Then again, maybe I am being a little harsh. What do you think? I wish I had the opportunity to walk or ride a bike to work everyday :( Thanks again for another thought provoking post. BTW, I still need to get that glucose meter so I can do some experiments of my own.<br /><br />JustinAnonymousnoreply@blogger.com